Neuroimmune Interaction Basics: Explores fundamental interactions between the nervous system and immune system, explaining their roles in maintaining health and contributing to disease.

Roles of Innate and Adaptive Immunity: Discusses the interaction between innate immune cells (like macrophages and dendritic cells) and adaptive immune cells (such as T-cells), which collectively defend against pathogens and maintain health.

Pattern Recognition and Immune Response: Details the function of pattern recognition receptors, including Toll-like receptors, which recognize pathogens and initiate immune responses crucial for combating infections.

Complement System Activation: Explains the activation mechanisms of the complement system, highlighting its role in immune surveillance and response through the classical, lectin, and alternative pathways.

Cytokine Dynamics: Reviews how cytokines regulate immune and inflammatory responses, emphasizing their impact on neuroinflammation and potential connections to neurodegenerative conditions.

Neuroendocrine Immune Regulation: Outlines the regulation of immune responses by the neuroendocrine system, showing how hormones and neurotransmitters modulate the activity of immune cells.

Immune Mediators and Behavior: Explores how immune system mediators like cytokines can influence central nervous system functions and behavior, which may include effects on neurodevelopment and neuropsychiatric disorders.

Maternal Immune Activation: Discusses the impact of maternal immune activation on fetal brain development and links to neurodevelopmental disorders like autism, highlighting the role of cytokines such as interleukin-17.

Chronic Inflammation and Neurodevelopment: Considers how chronic gestational inflammation can alter brain development and behavior, with specific attention to the influence of interleukin-17 in the context of neurodevelopmental risks.

Glial Cells and Neuron-Glia Interactions: Reviews the roles of glial cells in the brain, focusing on their interactions with neurons and their crucial functions in synaptic maturation, plasticity, and overall CNS health.

Concept of the Disconnected Brain: Explores the theory that brain dysfunction in developmental disorders is often due to disconnections between key neural networks, rather than localized damage.

Role of Timing and Processing in the Brain: Discusses how precise timing and processing within various brain systems are crucial for coordinated activity and proper brain function.

Neuroscience Foundations: Reviews basic neuroscience principles that underpin our understanding of brain connectivity and function, with a focus on how disruptions can lead to disorders.

Neuroimmunology Insights: Explores the interplay between the nervous system and the immune system, detailing how immune responses can affect brain connectivity and function.

Neuroplasticity and Rehabilitation: Highlights the brain's ability to reorganize itself by forming new neural connections, which is crucial for recovery from brain disconnection.

Intervention Strategies: Introduces various therapeutic approaches aimed at restoring proper brain function through enhancing connectivity and synchronization across brain regions.

Case Studies and Practical Applications: Includes case studies (like Wesley's use of a letter board) that illustrate practical applications of theories and interventions in real-world settings.

Technological Advances in Treatment: Discusses the use of advanced technologies such as non-invasive spinal cord stimulation and its effects on brain processes and mood disorders.

Research and Future Directions: Covers ongoing research efforts and potential future directions in understanding and treating brain disconnections, with a focus on developmental and mood disorders.

Educational and Supportive Resources: Provides information on resources for further learning and support, emphasizing the importance of community and knowledge in managing brain disconnection syndromes.

Complex Interplay of Nervous and Immune Systems: Describes how the nervous and immune systems interact intricately to influence health, with a focus on neuroimmunological mechanisms.

Innate and Adaptive Immunity: Explains the roles and interactions between innate and adaptive immune responses, detailing specific cell types and immune pathways.

Role of Cytokines and Neuroinflammation: Discusses the effects of cytokines like IL-17 and TNF-alpha on neuroinflammation, and their links to neurodevelopmental and neurodegenerative diseases.

Impact of Maternal Factors on Development: Reviews how maternal immune activation and other maternal factors influence fetal brain development and the risk of neurodevelopmental disorders such as autism.

Behavioral and Neurological Consequences of Immune Activation: Explores how immune system dysfunction, particularly in the context of maternal health, can lead to behavioral and neurological changes in offspring.

Microglia and Glia Interactions in CNS: Highlights the role of microglia and other glial cells in maintaining CNS health, their involvement in synaptic pruning, and the implications for neurological diseases.

Functional Anatomy of the Brain: Provides insights into brain anatomy and functionality, emphasizing the significance of Brodmann areas and their role in various brain functions.

Neuroinflammation and Psychiatric Disorders: Discusses the relationship between neuroinflammation and psychiatric conditions, including anxiety and OCD, and how stress affects this interplay.

Neuroimmunology of Stress and Anxiety: Examines the specific pathways through which stress and anxiety impact neuroimmune interactions and contribute to the symptoms of neurodevelopmental disorders.

Therapeutic and Integrative Approaches: Introduces therapeutic strategies for addressing the imbalances in neuroimmune interactions, including approaches to enhance brain integration and function.